Instrument :Biological molecular interaction analyzer

Model:BiacoreT200

Manufacturer：Cytiva

Application:Determination of the affinity between drugandtarget, antibody and antigen, high throughput screening of drugs and antibodies

Functions:

Based on the Surface Plasmon Resonance (SPR) technology, the biomolecular interaction analyzer is a classical technology for real-time and non-labeled study of dynamic interactions between biomolecules. Its advantages are real-time and dynamic observation of molecular interactions. In addition to the determination of strength of binding (affinity), it can also reflect the speed of molecular recognition and complex stability .

Technical specifications：

1、Detection principle: surface plasmon resonance(SPR)

2、Temperature control：4-45℃

3、Detecting refractive index range：1.33-1.40

4、Signal response dynamic range：1 – 70000 RU

5、Baseline noise：< 0.03 RU (1RU = 1pg/mm2= 1.6 pm)

6、Bindingrate constant range：103– 3 ×109M-1s-1

7、Dissociation rate constant range：10-5– 1 s-1

8、Equilibrium affinity constant range：103– 3 × 1014M-1

Functionary：Guoshuang，Guanxiangchen

Office phone：022-85358293

E-mail：guoshuang@nankai.edu.cn

guanxc@nankai.edu.cn

Communication address：Nankai UniversityJinnanCampus integrated laboratories building D320