Research Interest:
1) Total synthesis of structurally complicated natural products;
2) Synthesis, mode of action, medicinal, and translational study of bioactive natural products;
3) Interdisciplinary study of natural products.
Education History:
2001-2005,College of Sciences, Xi’an University of Architecture and Technology,Bachelor of Applied Chemistry
2008-2013,Shanghai Institute of Organic Chemistry (SIOC), Chinese Academy of Sciences (CAS), Doctor of Organic Chemistry
Honors and Awards
2022, Thieme Chemistry Journals Award
2013, CAS Presidential Scholarship, SIOC, CAS, Shanghai, China
2013, Shanghai Outstanding Graduate, SIOC, CAS, Shanghai, China
2012, National Scholarship, SIOC, CAS, Shanghai, China
Scientific Achievements & Selected Publications
1. C. Chong,† L. Chang,† I. Grimm,† Q. Zhang, Y. Kuang, B. Wang, J. Kang, W. Liu, J. Baars, Y. Guo, H.-G. Schmalz,* Z. Lu,* Divergent Total Synthesis of the Revised Structures of Marine Anti-Cancer Meroterpenoids (+)-Dysiherbols A–E, Chem. Sci. 2023, 14, 3302–3310. († these authors contributed equally)
2. C. Chong, Q. Zhang, J. Ke, H. Zhang, X. Yang, B. Wang, W. Ding, Z. Lu,* Total Synthesis of Anti‐Cancer Meroterpenoids Dysideanone B and Dysiherbol A and Structural Reassignment of Dysiherbol A, Angew. Chem. Int. Ed. 2021, 60, 13808–13813.
3. K. C. Nicolaou,* R. Li,† Z. Lu,† E. N. Pitsinos, L. B. Alemany, M. Aujay, C. Lee, J. Sandoval, J. Gavrilyuk, Streamlined Total Synthesis of Shishijimicin A and Its Application to the Design, Synthesis and Biological Evaluation of Analogues Thereof, and Practical Syntheses of PhthNSSMe and Related Sulfenylating Reagents, J. Am. Chem. Soc. 2018, 140, 12120–12136. († these authors contributed equally)
4. K. C. Nicolaou,* Z. Lu,† R. Li,† J. R. Woods, T. Sohn, Total Synthesis of Shishijimicin A, J. Am. Chem. Soc. 2015, 137, 8716–8719. († these authors contributed equally)
5. Z. Lu,† Y. Li,† J. Deng, A. Li,* Total Synthesis of the Daphniphyllum Alkaloid Daphenylline, Nature Chem. 2013, 5, 679–684. († these authors contributed equally)