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尚鲁庆 教授 Luqing Shang
Doctor degree, professor, State laboratory of Chemical Medical Biology
Special Talent:
Address: Nankai University, No.38 Tongyan Road, Haihe Education Park, Tianjin, 300350, People's Republic of China.
Telephone: +86-22-23506290
Email: shanglq@nankai.edu.cn
Research Group Website:

Research Interest

Chemical biology and medicinal chemistry of antiviral drug

Education History

2000-2004,  College of Pharmacy,  Shandong University, China, B.S., Shandong University, China, Bachelor of Pharmacy

2005-2006,  Research in Wakayama Medicinal University, Wakayama, Japan.

2004-2009,  College of Pharmacy,  Shandong University, China, Doctor of Medicinal Chemistry

Honors and Awards

 [1] 2022, Outstanding young talent Scholar

 [2]2016, Young Scientific and Technological Talents of Tianjin Innovation Talent Promotion Program

 

Scientific Achievements & Selected Publications

1.     Dong-Mei Li*, Lu-Qing Shang*, Comprehensive insights into the catalytic mechanism of Middle East Respiratory Syndrome 3C-like protease and Severe Acute Respiratory Syndrome 3C-like protease. ACS Catal. 2020, 10, 58715890.

2.     Lu-Qing Shang*, A Mitochondria-targeted fluorescent probe for monitoring NADPH overproduction during influenza virus infection. ACS Sens. 2023, 8,829-838.

3.     Ya-Xin Wang*, Lu-Qing Shang*. Application of dually activated Michael acceptor to the rational design of reversible covalent inhibitor for Enterovirus 71 3C protease. J. Med. Chem., 2019, 62, 6146-6162.

4.     Bing-He Wang*, Lu-Qing Shang*. 4Iminooxazolidin-2-one as a bioisostere of the cyanohydrin moiety: inhibitors of. enterovirus 71 3C protease. J. Med. Chem., 2018, 61, 22, 10333-10339.

5.     Yu Guo *, Bo Zhang*, Lu-Qing Shang*. The structure-based design of peptidomimetic inhibitors against SARS-CoV-2 3C Like protease as potent anti-viral drug candidate. Eur J Med Chem, 2022, 238, 114458.