Research Interest:
Chemical biology and medicinal chemistry of antiviral drug
Education History:
2000-2004, College of Pharmacy, Shandong University, China, B.S., Shandong University, China, Bachelor of Pharmacy
2005-2006, Research in Wakayama Medicinal University, Wakayama, Japan.
2004-2009, College of Pharmacy, Shandong University, China, Doctor of Medicinal Chemistry
Honors and Awards
[1] 2022, Outstanding young talent Scholar
[2]2016, Young Scientific and Technological Talents of Tianjin Innovation Talent Promotion Program
Scientific Achievements & Selected Publications
1. Dong-Mei Li*, Lu-Qing Shang*, Comprehensive insights into the catalytic mechanism of Middle East Respiratory Syndrome 3C-like protease and Severe Acute Respiratory Syndrome 3C-like protease. ACS Catal. 2020, 10, 5871−5890.
2. Lu-Qing Shang*, A Mitochondria-targeted fluorescent probe for monitoring NADPH overproduction during influenza virus infection. ACS Sens. 2023, 8,829-838.
3. Ya-Xin Wang*, Lu-Qing Shang*. Application of dually activated Michael acceptor to the rational design of reversible covalent inhibitor for Enterovirus 71 3C protease. J. Med. Chem., 2019, 62, 6146-6162.
4. Bing-He Wang*, Lu-Qing Shang*. 4‐Iminooxazolidin-2-one as a bioisostere of the cyanohydrin moiety: inhibitors of. enterovirus 71 3C protease. J. Med. Chem., 2018, 61, 22, 10333-10339.
5. Yu Guo *, Bo Zhang*, Lu-Qing Shang*. The structure-based design of peptidomimetic inhibitors against SARS-CoV-2 3C Like protease as potent anti-viral drug candidate. Eur J Med Chem, 2022, 238, 114458.