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帅领研究员 Ling Shuai
Ph.D., professor, State Key Laboratory of Chemical Medical Biology, graduated from Northeast Agricultural University, China National Science Found for Outstanding Young Scholars
Special Talent： Micromanipulation for embryos
Address： State Key Laboratory of Medicinal Chemical Biology Lab Hall (Flr.4, Rm. D420), Nankai university, No.38 Tongyan Rd., Jinnan Dist., 300350, China
Telephone： +86-022-85358291
Email： lshuai@nankai.edu.cn
Research Group Website： https://pharmacy.nankai.edu.cn/info/1011/1286.htm


Research Interest：Stem cells and Genetics

Education History：

2005-2009，College of life science, Northeast Agricultural University，Bachelor of Biological Science

2009-2013，College of life science, Northeast Agricultural University，Doctor of Biochemistry and Molecular Biology

Honors and Awards:

National Science Found for Outstanding Young Scholars

Scientific Achievements & Selected Publications

1.     Wenhao Zhang#, Chunmeng Yao#, Yanrui Luo#, Qian Li, Qian Zhao, Yiding Zhao, Yuna Wang, Mengyang Geng, Qing Wang, Mei Xu, Shengyi Sun, Dan Wu, Qian Gao, Xudong Wu*, Ling Shuai*. Rif1 and Hmgn3 Regulate the Conversion of Murine Trophoblast Stem Cells. Cell Reports, 2022, 38(13):110570.

2.     Jinxin Zhang#, Yiding Zhao, Yaru Tian, Mengyang Geng, Yan Liu*, Wenhao Zhang*, Ling Shuai*. Genome-wide Screening in the Haploid System Reveals Slc25a43 as a Target Gene of Oxidative Toxicity. Cell Death & Disease, 2022, 13(3):284.

3.     Mei Xu#, Yiding Zhao#, Wenhao Zhang#, Mengyang Geng, Qian Liu, Qian Gao*, Ling Shuai*. Genome-scale screening in a rat haploid system identifies Thop1 as a modulator of pluripotency exit, Cell Proliferation, 2022, 55(4):e13209.

4.     Qian Gao#, Wenhao Zhang#, Yiding Zhao#, Yaru Tian, Yuna Wang, JInxin Zhang, Mengyang Geng, Mei Xu, Chunmeng Yao, Haoyu Wang, LuyuanLi*, Yan Liu*, Ling Shuai*. High-throughput screening in postimplantation haploid epiblast stem cells reveals Hs3st3b1 as a modulator for reprogramming, Stem Cells Translational Medicine, 2021, 10(5): 743-755.

5.     Wenhao Zhang#, Yaru Tian#, Qian Gao#, Xu Li, Yanni Li, Jinxin Zhang, Chunmeng Yao, Yuna Wang, Haoyu Wang, Yiding Zhao, Qian Zhang, Luyuan Li, Yang Yu*, Yong Fan*, Ling Shuai*. Inhibition of Apoptosis Reduces Diploidization of Haploid Mouse Embryonic Stem Cells during Differentiation, Stem Cell Reports, 2020, 15(1): 185-197.

6.     Keli Peng#, Xu Li#, Congyu Wu#, Yuna Wang, Jian Yu, Jinxin Zhang, Qian Gao, Wenhao Zhang, Qian Zhang, Yong Fan, Yang Yu, Ling Shuai*. Derivation of haploid trophoblast stem cells via conversion in vitro. iScience, 2019, 11: 508-518.

7.     Haisong Wang#, Wenhao Zhang, Jian Yu, Congyu Wu, Qian Gao, Xu Li, Yanni Li, Jinxin Zhang, Yaru Tian, Tao Tan, Weizhi Ji, Luyuan Li, Yang Yu, Ling Shuai*. Genetic screening and multipotency in rhesus monkey haploid neural progenitor cells. Development, 2018, 145(11).