Research Interest:
a) Development of new reactions occurring in a catalytic and selective manner by the design of transition metal-catalysts and ligands, especially focusing on reactions that form carbon-main element bonds, and exploration of these reactions in addressing challenges in traditional organic transformations, e.g., establishment of multiple chiral centers in a single step, reactions forming all-carbon stereogenic centers;
b) Synthesis of natural products and biologically active molecules, and exploration of their medicinal applications.
Education History:
2004-2008,Zhengzhou University,Department of Chemistry, Bachelor degree
2008-2013,Nankai University,Department of Chemistry, Ph.D.
2013-2015,Peking University,Department of Chemistry, Postdoc (With Prof. Z. J. Shi)
2016-2020,UC Berkeley,Department of Chemistry, Postdoc (With Prof. John. F. Hartwig)
Honors and Awards
Scientific Achievements & Selected Publications
1. Kang, J.; Ding, K.; Ren, S.-M.; Su, B.*, Copper-Catalyzed Dynamic Kinetic Asymmetric P-C Coupling of Secondary Phosphine Oxides and Aryl iodides. Angew. Chem. Int. Ed. 2023, 62, e202301628.
2. Su, B.*; Hartwig, J. F.*, Development of Chiral Ligands for the Transition-Metal-Catalyzed Enantioselective Silylation and Borylation of C−H Bonds. Angew. Chem. Int. Ed. 2022, 61, e202113343.
3. Su, B.; Bunescu, A.; Qiu, Y.; Zuend, S. J.; Ernst, M.; Hartwig, J. F.*, Palladium-Catalyzed Oxidation of β-C(sp3)–H Bonds of Primary Alkylamines through a Rare Four-Membered Palladacycle Intermediate. J. Am. Chem. Soc. 2020, 142, 7912-7919.
4. Xi, Y. #; Su, B#.; Qi, X.; Pedram, S.; Liu, P.; Hartwig, J. F. *, Application of Trimethylgermanyl-Substituted Bisphosphine Ligands with Enhanced Dispersion Interactions to Copper-Catalyzed Hydroboration of Disubstituted Alkenes. J. Am. Chem. Soc. 2020, 142, 18213-18222. (#Co-first author)
5. Oeschger, R. #; Su, B. #; Yu, I.; Ehinger, C.; Romero, E.; He, S.; Hartwig, J.*, Diverse functionalization of strong alkyl C–H bonds by undirected borylation. Science 2020, 368, 736-741. (#Co-first author)
6. Su, B.; Hartwig, J. F.*, Iridium-Catalyzed, Silyl-Directed, peri-Borylation of C−H Bonds in Fused Polycyclic Arenes and Heteroarenes. Angew. Chem. Int. Ed. 2018, 57, 10163-10167.
7. Su, B.; Lee, T.; Hartwig, J. F.*, Iridium-Catalyzed, β-Selective C(sp3)–H Silylation of Aliphatic Amines To Form Silapyrrolidines and 1,2-Amino Alcohols. J. Am. Chem. Soc. 2018, 140, 18032-18038.
8. Su, B.; Hartwig, J. F.*, Ir-Catalyzed Enantioselective, Intramolecular Silylation of Methyl C–H Bonds. J. Am. Chem. Soc. 2017, 139, 12137-12140.
9. Su, B.; Zhou, T.-G.; Xu, P.-L.; Shi, Z.-J.; Hartwig, J. F., Enantioselective Borylation of Aromatic C−H Bonds with Chiral Dinitrogen Ligands. Angew. Chem. Int. Ed. 2017, 56 (25), 7205-7208.
10. Su, B.; Zhou, T.-G.; Li, X.-W.; Shao, X.-R.; Xu, P.-L.; Wu, W.-L.; Hartwig, J. F.*; Shi, Z.-J.*, A Chiral Nitrogen Ligand for Enantioselective, Iridium-Catalyzed Silylation of Aromatic C−H Bonds. Angew. Chem. Int. Ed. 2017, 56, 1092-1096.