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郗日沫 研究员 Rimo Xi
Professor, College of Pharmacy, State laboratory of Chemical Medical Biology, Nankai University
Special Talent:
Address: Room 315, Building of Pharmacy, 38 Tongyan Road, Haihe Education District, Tianjin, 300353
Telephone:
Email: xirimo@nankai.edu.cn
Research Group Website: https://pharmacyen.nankai.edu.cn/info/1019/1044.htm

Education:

MBA(1998-1999): Management, Business School of University of Wisconsin-Madison, USA.

Postdoc. (1997-1998): Chemistry, University of Wisconsin-Madison, USA.

Postdoc. (1995-1997): Chemistry, University of Chicago, Chicago, USA.

Ph.D.(1992-1995): Chemistry, Institute for Molecular Science, Okazaki, Japan.

M.S.(1984-1987): Chemistry, Nankai University, Tianjin, China.

B.S.(1980-1984): Chemistry, Nankai University, Tianjin, China.

Research History:

Nankai University (2009-present), Tianjin, China. Professor, College of Pharmacy

Shandong University (2003-2009), Shandong, Jinan, China. Professor, The School of Chemistry and Chemical Engineering

Biotech Atlantic Inc. (1999-2003), Eatontown, NJ, USA. Vice President, R&D Department

University of Wisconsin-Madison (1997-1998), Madison, WI, USA. Postdoctoral Research Associate – The Department of Chemistry

The University of Chicago (1995-1997), Chicago, IL, USA. Postdoctoral Research Associate – The Department of Chemistry

Institute for Molecular Science (1992-1995), Okazaki, Japan. Ph.D. Candidate, The Physical and Mathematical Department

Peking University (1987-1990), Beijing, China. Research Associate, Department of Chemistry 

Research Interest:

Antibody-based Drug Development and Biochemical Analysis (immunoassay; fluorescent/raman assay); Molecular biological assay of drug resistance

Scientific Achievements Selected Publications

1.   Wenting Liu, Jianhao Di, Yan Ma, Shuo Wang, Meng Meng, Yongmei Yin*, Rimo Xi* and Xiujie Zhao*, A Mitochondria-Mediated HSPs inhibition strategy for Enhanced Low-Temperature Photothermal Therapy, ACS Applied Materials & Interfaces 2023.

2.   Xiujie Zhao, Hongjie Zhao, Shuo Wang, Zhiwen Fan, Yan Ma, Yongmei Yin, Wei Wang, Rimo Xi,* and Meng Meng*, A Tumor-Targeting Near-Infrared Heptamethine Cyanine Photosensitizer with Twisted Molecular Structure for Enhanced Imaging-Guided Cancer Phototherapy, J. Am. Chem. Soc. 2021, 143, 20828−20836.

3.   Yanqi QiaoYan MaYue TongWenting LiuShuo WangYing ZhengChangjun MenJie YuJie PanDong WanYongmei YinXiujie ZhaoRimo Xi*Meng Meng*, Phototherapy and Mechanism Exploration of Biofilm and Multidrug-Resistant Helicobacter pylori by Bacteria-Targeted NIR Photosensitizer, Small, 2023, 19(4):e2205248

4.   Bei WangQi GanYue TongYanqi QiaoMengfan HanRuixiao ZhangQuansheng HanChuanbing LiSu BaiLong XuYongmei YinChunze ZhangBaatar MunkhtsetsegXiujie ZhaoMeng Meng*, Rimo Xi*, A visual diagnostic detection of Helicobacter pylori and the gastric carcinoma-related virulence genes (cagA and vacA) by a fluorescent loop-mediated isothermal amplification (LAMP), Talanta 256 (2023):124260

5.   Kai Wang, Ruixiao Zhang, Xiujie Zhao*, Yan Ma, Lijun Ren, Youxiao Ren, Gaofei Chen, Dingming Ye, Jinfang Wu, Xinyuan Hu, Yuanqiang Guo, Rimo Xi, Meng Meng, Qingqiang Yao*, Ping Li*, Qixin Chen,* and Tony D. James*, Reversible Recognition-Based Boronic Acid Probes for Glucose Detection in Live Cell and Zebrafish, J. Am. Chem. Soc. 2023 (in press)

6.   Xueni Zhang; Lihui Dai; Yumeng Ding; Qian Liu; Xiaoya Li; Mengting Liu; MengMeng; JiePan*; Rimo Xi*; Yongmei Yin*, An MMP-2 Sensitive and Reduction-responsive Prodrug Amphiphile for Actively Targeted Therapy of Cancer by Hierarchical Cleavage, Chem. Comm. 2022,59(7): 900-903

7.   Xiujie Zhao,*§ Shuo Wang § Yan Ma, Wenting Liu, Hongjie Zhao, Jianhao Di, Zhiwen Fan, Yongmei Yin, Ying Zheng, Rimo Xi,* and Meng Meng*, Synergistic Release of Photothermal Molecules from Nanocarriers Induced by Light and Hyperthermia Benefits Efficient Anticancer Phototherapy, Anal. Chem. 2022, 94, 17160−17168 (§ X.Z. and S.W. contributed equally to this work).

8.   Ying Zhang, Qian Liu, Mengting Liu, Xueni Zhang, Xiaoya Li, Lihui Dai, Meng Meng, Dingbin Liu, Yongmei Yin*, Rimo Xi*, Dual functional molecule aided background-free SERS sensor for intracellular pH dynamic monitoring based on foldable DNA transition, Sensors & Actuators: B. Chemical 353 (2022) 131162.

9.   Qian Liu, Fang Wu, Huixia Di, Yingna Bi, Meng Meng, Dingbin Liu, Yongmei Yin*, Rimo Xi*, A novel SERS biosensor for ultrasensitive detection of mercury(II) in complex biological samples, Sensors & Actuators: B. Chemical 351 (2022) 130934.