Doctor degree, professor, State laboratory of Medical Chemical Biology and College of Life Sciences, Nankai University. Graduated from Hong Kong University.
National Science Found for Distinguished Young Scholars
Research Interest：The controllable peptide self-assembly and its biomedical applications.
Education History：
1997.09-2001.07, Department of Polymer science, Bachelor student, Nanjing University.
2001.07-2002.12, Department of Polymer science, Research Assistant, Nanjing University.
2003.02-2006.08, Department of Chemistry, Ph.D., Hong Kong University of Science and Technology.
Honors and Awards
Ÿ Chief Scientist for Major Research and Development Programs
Ÿ National Science Fund for Distinguished Young Scholars, 2018
Ÿ First Prize of Tianjin Natural Science (1/11), 2015
Scientific Achievements & Selected Publications
1. Ding, Y.#; Zheng, D.#; Xie, L.; Zhang, X.; Zhang, Z.; Wang, L.; Hu, Z.*; Yang, Z*, Enzyme-Instructed Peptide Assembly Favored by Preorganization for Cancer Cell Membrane Engineering, J. Am. Chem. Soc., 2023, 145 (8): 4366-4371 (select as front cover).
2. Yu, H.#; Shang, Y.#; Sun W.#; Ouyang, X.; Zhou, W.; Lu, J.; Yang, S.; Wei, W.; Yao, X.; Wang, X.; Zhang, X.; Chen, Y.; He, Q.; Yang, Z.*, Ouyang, H.*Seamless and early gap healing of osteochondral defects by autologous mosaicplasty combined with bioactive supramolecular nanofiber-enabled gelatin methacryloyl (BSN-GelMA) hydrogel, Bioact. Mater., 2023, 19, 88-102.
3. Zheng, D.; Liu, J.; Xie, L.; Wang, Y.; Ding, Y.; Peng, R.; Cui, M.; Wang, L.; Zhang, Y.*; Zhang, C.*; Yang, Z.*; Enzyme-instructed and mitochondria-targeting peptide self-assembly to efficiently induce immunogenic cell death, Acta Pharm. Sin. B., 2022, 12 (6), 2740-2750.
4. Zhan, J.; Wang, Y.; Ma, S.; Qin, Q.; Wang, L.; Cai, Y.*; Yang, Z.*; Organelle-inspired supramolecular nanomedicine to precisely abolish liver tumor growth and metastasis, Bioact. Mater., 2022, 9, 120-133.
5. Wang, Y.; Li, X.; Zheng, D.; Chen, Y.; Zhang, Z.; Yang, Z.*; Selective Degradation of PD-L1 in Cancer Cells by Enzyme-Instructed Self-Assembly, Adv. Funct. Mater., 2021, 31, 2102505.
6. Li, X.; Wang, Y.; Zhang, Y.; Liang, C.; Zhang, Z.; Chen, Y.; Hu, Z.*; Yang, Z.*; A Supramolecular “Trident” for Cancer Immunotherapy, Adv. Funct. Mater., 2021, 31, 2100729.
7. Chen, Y.; Zhang, W.; Liang, C.; Zheng, D.; Wang, Y.; Li, X.; Shi, Y.; Wang, F.*; Dong, W.*; Yang, Z.*, Supramolecular nanofibers with superior anti-angiogenesis and antitumor properties by enzyme-instructed self-assembly (EISA), Chem. Eng. J., 2021, 425, 130531.
8. Liu, M.#; Wang, Z.#; Feng, D.; Shang, Y.; Li, X.; Liu, J.*; Yang, Z.*; An Insulin-Inspired Supramolecular Hydrogel for Prevention of Type 1 Diabetes, Adv. Sci., 2021, 8, 2003599.
9. Zhang, Z.; Ai, S.; Yang, Z.*; Li, X.*; Peptide-based supramolecular hydrogels for local drug delivery, Adv. Drug Deliv. Rev., 2021, 174, 482-503.
10. Zhong, Y.; Zhan, J.*; Xu, G.; Chen, Y.; Qin, Q.; Liao, X.; Ma, S.; Yang, Z.*; Cai, Y.*; Enzyme-Instructed Self-Assembly Enabled Monomer-Excimer Transition to Construct Higher Ordered Luminescent Supramolecular Assembly for Activity-based Bioimaging, Angew Chem., 2021, 60, 8121-8129.
11. Shang, Y.; Liu, H.; Peng, R.; Ren, C.; Luo, X.; Ma, C.; Gao, Y; Wang, Z.*; Gao, J.*; Liu, J.*; Yang, Z.*; PDGF-mimicking Supramolecular Nanofibers for Ionizing Radiation-induced Injury Repair, Chem. Eng. J., 2021, 410, 128309.
12. Gao, J.; Zhan, J.; Yang, Z.*; Enzyme-Instructed Self-Assembly (EISA) and Hydrogelation of Peptides, Adv. Mater., 2020, 32, 1805798.
13. Zheng, D.; Chen, Y.; Ai, S.; Zhang, R.; Gao, Z.; Liang, C.; Cao, L.; Chen, Y.; Hong, Z.; Shi, Y.; Wang, L.; Li, X.*; Yang, Z.*; Tandem Molecular Self-Assembly Selectively Inhibits Lung Cancer Cells by Inducing Endoplasmic Reticulum Stress, Research, 2019, 4, 1-11.
14. Shang, Y.#; Zhi, D.#; Feng, G.; Wang, Z.; Mao, D.; Guo, S.; Liu, R.; Liu, L.; Zhang, S.; Sun, S.; Wang, K.*; Kong, D.; Gao, J.*; Yang, Z.*; Supramolecular Nanofibers with Superior Bioactivity to IGF-1, Nano Lett., 2019, 19, 1560-1569.
15. Zhan, J.; Cai, Y.; He, S.; Wang, L.; Yang, Z.*; Tandem Molecular Self‐Assembly in Liver Cancer Cells, Angew Chem., 2018, 57, 1813-1816.
