Research Interest：
Cytoskeletal basis and signaling mechanism of development and disease
Education History：
1992-1997，College of Life Sciences, Fudan University，B.S. in Genetics
1997-1999，College of Life Sciences, Peking University，Master’s student in Cell Biology
1999-2002，Graduate Division of Biological and Biomedical Sciences, Emory University，Ph.D. in Cell Biology
Honors and Awards
Scientific Achievements & Selected Publications
1. Wei Xie, Siqi Gao, Yunfan Yang, Hongjie Li, Junyan Zhou, Mingzhen Chen, Song Yang, Yijun Zhang, Liang Zhang, Xiaoqian Meng, Songbo Xie, Min Liu, Dengwen Li, Yan Chen, Jun Zhou. CYLD deubiquitinates plakoglobin to promote Cx43 membrane targeting and gap junction assembly in the heart. Cell Reports 2022. 41(13):111864.
2. Tao Zhong, Xiaofan Wu, Wei Xie, Xiangrui Luo, Ting Song, Shuang Sun, Youguang Luo, Dengwen Li, Min Liu, Songbo Xie, Jun Zhou. ENKD1 promotes epidermal stratification by regulating spindle orientation in basal keratinocytes. Cell Death & Differentiation 2022. 29(9):1719-1729.
3. Yang Yang, Miao Chen, Jingrui Li, Renjie Hong, Jia Yang, Fan Yu, Te Li, Song Yang, Jie Ran, Chunyue Guo, Yi Zhao, Yi Luan, Min Liu, Dengwen Li, Songbo Xie, Jun Zhou. A cilium-independent role for intraflagellar transport 88 in regulating angiogenesis. Science Bulletin 2021. 66(7):727-739.
4. Jie Ran, Min Liu, Jie Feng, Haixia Li, Huixian Ma, Ting Song, Yu Cao, Peng Zhou, Yuhan Wu, Yunfan Yang, Yang Yang, Fan Yu, Heng Guo, Liang Zhang, Songbo Xie, Dengwen Li, Jinmin Gao, Xiaomin Zhang, Xueliang Zhu, Jun Zhou. ASK1-mediated phosphorylation blocks HDAC6 ubiquitination and degradation to drive the disassembly of photoreceptor connecting cilia. Developmental Cell 2020. 53(3):287-299.
5. Fan Yu, Song Guo, Te Li, Jie Ran, Wei Zhao, Dengwen Li, Min Liu, Xiumin Yan, Xiaoyong Yang, Xueliang Zhu, Jun Zhou. Ciliary defects caused by dysregulation of O-GlcNAc modification are associated with diabetic complications. Cell Research 2019. 29(2):171-173.
