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朱春雷 研究员Chunlei Zhu
Doctor degree, professor, State laboratory of Chemical Medical Biology, graduated from Institute of Chemistry, Chinese Academy of Sciences (with Prof. Shu Wang)
Special Talent： National Youth Talent Plan
Address： 94 Weijin Rd, Tianjin 300071, China
Telephone：
Email： chunlei.zhu@nankai.edu.cn
Research Group Website： https://www.x-mol.com/groups/zhu_chunlei

Research Interest：

Design and synthesis of functional materials for antimicrobial treatment, antibiotics screening, biosensing, and cancer therapy.

Education History：

2004-2008，Department of Chemistry, Jilin University，Bachelor of Chemistry

2008-2013，Institute of Chemistry, Chinese Academy of Sciences，Doctor of Organic Chemistry

Honors and Awards：

•       Nanoscale Emerging Investigator (2021), Royal Society of Chemistry

•       Journal of Materials Chemistry B (2021), Royal Society of Chemistry

Scientific Achievements & Selected Publications

1.   Shuyi Lv, Chao Wang, Ke Xue, Jiaxin Wang, Ming-hui Xiao, Zhencheng Sun, Lei Han, Linqi Shi, and Chunlei Zhu,* Activated alkyne-enabled turn-on click bioconjugation with cascade signal amplification for ultrafast and high-throughput antibiotic screening, Proc. Natl. Acad. Sci. U.S.A. 2023, 120, e2302367120.

2.   Xiaolin Liu,* Chunlei Zhu,* and Ben Zhong Tang,* Informatics colourizes polymers, Nat. Rev. Chem. 2023, 7, 232-233.

3.   Hao Fu, Ke Xue, Yongxin Zhang, Ming-hui Xiao, Kaiyu Wu, Linqi Shi, and Chunlei Zhu,* Thermoresponsive hydrogel-enabled thermostatic photothermal therapy for enhanced healing of bacteria-infected wounds. Adv. Sci. 2023, 10, 2206865.

4.   Binghong He#, Chao Wang#, Fuping Wang, Liang Tian, Haitao Wang, Chunling Fu, Jin Liu, Chao Xi, Chunlei Zhu,* and Qiong Yang,* Differentiation therapy for murine myelofibrosis model with MLN8237 loaded low-density lipoproteins, J. Control. Release 2023, 356, 554-566.

5.   Jiaxin Wang, Boyi Hao, Ke Xue, Hao Fu, Minghui Xiao, Yongxin Zhang, Linqi Shi, and Chunlei Zhu,* A smart photothermal nanosystem with an intrinsic temperature-control mechanism for thermostatic treatment of bacterial infections, Adv. Mater. 2022, 34, 2205653.

6.   Xiaolin Liu, Chunlei Zhu,* and Ben Zhong Tang,* Bringing inherent charges into aggregation-induced emission research, Acc. Chem. Res. 2022, 55, 197-208.

7.   Xiaolin Liu,* Jianhui Liu, and Chunlei Zhu,* NIR-II organic dyes: Get brighter and see clearer, Matter 2022, 5, 3583-3585.

8.   Ke Xue#, Cuihong Yang#, Chun Wang, Yang Liu, Jianfeng Liu,* Linqi Shi,* and Chunlei Zhu,* An exceptional broad-spectrum nanobiocide for multimodal and synergistic inactivation of drug-resistant bacteria, CCS Chem. 2022, 4, 272-285.

9.   Boyi Hao, Jiaxin Wang, Chao Wang, Ke Xue, Minghui Xiao, Shuyi Lv, and Chunlei Zhu,* Bridging D‒A type photosensitizers with the azo group to boost intersystem crossing for efficient photodynamic therapy, Chem. Sci. 2022, 13, 4139-4149.

10. Ke Xue, Chao Wang, Jiaxin Wang, Shuyi Lv, Boyi Hao, Chunlei Zhu,* and Ben Zhong Tang,* A sensitive and reliable organic fluorescent nanothermometer for noninvasive temperature sensing, J. Am. Chem. Soc. 2021, 143, 14147-14157.

11. Xiaolin Liu#, Minghui Xiao#, Ke Xue, Mingzhao Li, Dongming Liu, Yong Wang, Xinzhe Yang, Yubing Hu, Ryan T. K. Kwok, Anjun Qin, Chunlei Zhu,* Jacky W. Y. Lam,* and Ben Zhong Tang,* Heteroaromatic hyperbranched polyelectrolytes: Multicomponent polyannulation and photodynamic biopatterning, Angew. Chem. Int. Ed. 2021, 60, 19222-19231.

12. Libei Huang, Siyu Xu, Zhaoyu Wang, Ke Xue, Jianjun Su, Yun Song, Sijie Chen, Chunlei Zhu,* Ben Zhong Tang,* and Ruquan Ye,* Self-reporting and photothermally enhanced rapid bacterial killing on a laser-induced graphene mask, ACS Nano 2020, 14, 12045-12053.

13. Chunlei Zhu#, Suphannee Pongkitwitoon#, Jichuan Qiu, Stavros Thomopoulos, and Younan Xia,* Design and fabrication of a hierarchically structured scaffold for tendon-to-bone repair, Adv. Mater. 2018, 30, 1707306.

14. Chunlei Zhu#, Jichuan Qiu#, Suphannee Pongkitwitoon#, Stavros Thomopoulos, and Younan Xia,* Inverse opal scaffolds with gradients in mineral content for spatial control of osteogenesis, Adv. Mater. 2018, 30, 1706706.

15. Chunlei Zhu and Younan Xia,* Biomimetics: reconstitution of low-density lipoprotein for targeted drug delivery and related theranostic applications, Chem. Soc. Rev. 2017, 46, 7668-7682.

16. Chunlei Zhu, Pallab Pradhan, Da Huo, Jiajia Xue, Song Shen, Krishnendu Roy, and Younan Xia,* Reconstitution of low density lipoproteins with fatty acids for the targeted delivery of drugs into cancer cells, Angew. Chem. Int. Ed. 2017, 56, 10399-10402.

17. Chunlei Zhu, Da Huo, Qiaoshan Chen, Jiajia Xue, Song Shen, and Younan Xia,* A eutectic mixture of natural fatty acids can serve as the gating material for near-infrared-triggered drug release, Adv. Mater. 2017, 29, 1703702.

18. Chunlei Zhu, Qiong Yang,* Fengting Lv, Libing Liu, and Shu Wang,* Conjugated polymer-coated bacteria for multimodal intracellular and extracellular anticancer activity, Adv. Mater. 2013, 25, 1203-1208.

19. Chunlei Zhu, Libing Liu, Qiong Yang, Fengting Lv, and Shu Wang,* Water-soluble conjugated polymers for imaging, diagnosis, and therapy, Chem. Rev. 2012, 112, 4687-4735.

20. Chunlei Zhu, Qiong Yang,* Libing Liu, and Shu Wang,* Rapid, simple and high-throughput antimicrobial susceptibility testing and antibiotics screening, Angew. Chem. Int. Ed. 2011, 50, 9607-9610.

21. Chunlei Zhu, Qiong Yang,* Libing Liu, Fengting Lv, Shayu Li, Guoqiang Yang, and Shu Wang,* Multifunctional cationic poly(p-phenylene vinylene) polyelectrolytes for selective recognition, imaging and killing of bacteria over mammalian cells, Adv. Mater. 2011, 23, 4805-4810.