Research Interest:
(1) Molecular mechanisms of lipid metabolism and transport and pathogenesis of related diseases;
(2) Molecular mechanisms of membrane shaping and remodeling and the pathogenesis of related diseases;
Education History:
2005-2009,College of Life Sciences, Nankai University,Bachelor of Biology
2009-2014,College of Life Sciences, Nankai University,Doctor of Cell Biology
Honors and Awards
Scientific Achievements & Selected Publications
(1) Yunyun Wang; Zhenni Li; Xinyu Wang; Ziyuan Zhao; Li Jiao; Ruming Liu; Keying Wang; Rui Ma; Yang Yang; Guo Chen; Yong Wang#; Xin Bian#; Insights into membrane association of the SMP domain of extended synaptotagmin, Nature Communications, 2023, 14(1);
(2) Jinghua Ge*; Xin Bian*; Lu Ma*; Yiying Cai*; Yanghui Li*; Jie Yang; Erdem Karatekin; Pietro De Camilli; Yongli Zhang; Stepwise membrane binding of extended synaptotagmins revealed by optical tweezers, Nature Chemical Biology, 2022, 18(3): 313-320;
(3) Xin Bian*; Zhao Zhang*; Qiancheng Xiong; Pietro De Camilli#; Chenxiang Lin#; A programmable DNA-origami platform for studying lipid transfer between bilayers, Nature Chemical Biology, 2019, 15(8): 830-837;
(4) Xin Bian; Yasunori Saheki#; Pietro De Camilli#; Ca2+ releases E-Syt1 autoinhibition to couple ER-plasma membrane tethering with lipid transport, The EMBO Journal, 2018, 37(2): 219-234;
(5) Xin Bian*; Robin W. Klemm*; Tina Y. Liu*; Miao Zhang; Sha Sun; Xuewu Sui; Xinqi Liu#; Tom A. Rapoport#; Junjie Hu#; Structures of the atlastin GTPase provide insight into homotypic fusion of endoplasmic reticulum membranes, Proceedings of the National Academy of Sciences, 2011, 108(10): 3976-3981.