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丁丹 教授Dan DING
Special Talent: Organic/Polymer Synthesis; Peptide Synthesis; Self-assembly; Nanotechnology; Chemical/Cell Biology; Disease Theranostics; Immunotherapy
Address: Institute of Molecular Biology #210, Nankai University, 94 Weijin Road, Tianjin 300071
Telephone: +86-22-23501229
Email: dingd@nankai.edu.cn
Research Group Website: www.dinglab.net

Research Interest

Design and synthesis of smart/functional materials and exploration of their biomedical applications

Education History

2001-2005College of Chemistry and Chemical Engineering, Nanjing University, Bachelor of Science

2005-2010College of Chemistry and Chemical Engineering, Nanjing University, Doctor of Science

Honors and Awards

1. Tianjin Youth Science and Technology Award (2019)

Scientific Achievements & Selected Publications

1.   Gao, Z.;# Jia, S.;# Ou, H.; Hong, Y.; Shan, K.; Kong, X.; Wang, Z.; Feng, G.; Ding, D.* An Activatable Near-Infrared Afterglow Theranostic Prodrug with Self-Sustainable Magnification Effect of Immunogenic Cell Death. Angewandte Chemie International Edition 2022, 61, e202209793.

2.   Qi, J.;# Jia, S.;# Kang, X.; Wu, X.; Hong, Y.; Shan, K.; Kong, X.; Wang, Z.; Ding, D.* Semiconducting Polymer Nanoparticles with Surface-Mimicking Protein Secondary Structure as Lysosome-Targeting Chimaeras for Self-Synergistic Cancer Immunotherapy. Advanced Materials 2022, 34, 2203309.

3.   Duan, X.;# Zhang, Q.;# Jiang, Y.; # Wu, X.; Xin, Y.; Geng, Y.; * Shen, J.; * Ding, D.* Semiconducting Polymer Nanoparticles with Intramolecular Motion-Induced Photothermy for Tumor Phototheranostics and Tooth Root Canal Therapy. Advanced Materials 2022, 34, 2200179.

4.   Chen, C.;# Gao, H.;# Ou, H.; # Kwok, R.; Tang, Y.; Zheng, D.; Ding, D.* Amplification of Activated Near-Infrared Afterglow Luminescence by Introducing Twisted Molecular Geometry for Understanding Neutrophil-Involved Diseases. Journal of the American Chemical Society 2022, 144 (8), 3429-3441.

5.   Xiao, F.; Gao, H.; Lei, Y.;* Dai, W.; Liu, M.; Zheng, X.; Cai, Z.; Huang, X.;* Wu, H.; Ding, D.* Guest-Host Doped Strategy for Constructing Ultralong-Lifetime Near-Infrared Organic Phosphorescence Materials for Bioimaging. Nature Communications 2022, 13, 186.

6.   Li, J.;# Fang, Y.;# Zhang, Y.; Wang, H.; Yang, Z.; Ding, D.* Supramolecular Self-Assembly-Facilitated Aggregation of Tumor-Specific Transmembrane Receptors for Signaling Activation and Converting Immunologically Cold to Hot Tumor, Advanced Materials 2021, 33, 2008518.

7.   Feng, G.; Zhang, G. Q.; Ding, D.* Design of Superior APhototheranostic Agents Guided by Jablonski Diagrams, Chemical Society Reviews 2020, 49, 8179-8234.

8.   Chen, C.;# Ou, H.;# Liu, R.; Ding, D.* Regulating the Photophysical Property of Organic/Polymer Optical Agents for Promoted Cancer Phototheranostics. Advanced Materials 2020, 32, 1806331.

9.   Chen, C.;# Ni, X.;# Tian, H. W.; Liu, Q.; Guo, D. S.; Ding, D.* Calixarene-Based Supramolecular AIE Dots with Highly Inhibited Nonradiative Decay and Intersystem Crossing for Ultrasensitive Fluorescence Image-Guided Cancer Surgery, Angewandte Chemie International Edition 2020, 59, 10008-10012.

10. Chen, C.;# Ni, X.;# Jia, S.; Liang, Y.; Wu, X.; Kong, D.; Ding, D.* Massively Evoking Immunogenic Cell Death by Focused Mitochondrial Oxidative Stress using an AIE Luminogen with a Twisted Molecular Structure. Advanced Materials 2019, 31, 1904914.