Research Interest:
Structural and mechanistic studies of key membrane proteins in fundamental biological processes, especially ion channels and transporters those closely related to human diseases, providing structural basis for drug development.
Education History:
2004-2008,School of Life Sciences, Anhui University,Bachelor of Biology.
2008-2013,School of Life Sciences, University of Science and Technology of China, Doctor of Biochemistry and Molecular Biology.
Honors and Awards
Scientific Achievements & Selected Publications
1. Dan-dan Qian#, Ye Cong#, Run-hao Wang, Quan Chen*, Chuang-ye Yan*, De-shun Gong*, Structural insight into the human SID1 transmembrane family member 2 reveals its lipid hydrolytic activity, Nature Communications 2023, 14, 3568
2. Dong-liang Liu#, Dan-dan Qian#, Huai-zong Shen, De-shun Gong*, Structure of the human Meckel-Gruber protein Meckelin, Science Advances 2021,7, eabj9748
3. De-shun Gong*#, Xi-min Chi#, Jin-hong Wei#, Ge-wei Zhou, Gao-xingyu Huang, Lin Zhang, Rui-wu Wang, Jian-lin Lei, S.R.-Wayne Chen*, Nieng Yan*, Modulation of cardiac ryanodine receptor 2 by calmodulin, Nature 2019, 572, 347-351
4. De-shun Gong*#, Xi-min Chi#, Kang Ren#, Gao-xingyu Huang, Ge-wei Zhou, Nieng Yan, Jian-lin Lei, Qiang Zhou*, Nature Communications 2018, 9, 3623
5. Xi-min Chi#, De-shun Gong*#, Kang Ren, Ge-wei Zhou, Gao-xingyu Huang, Jian-lin Lei, Qiang Zhou, Nieng Yan*, Proc Natl Acad Sci U S A 2019, 116, 25575-25582
6. De-shun Gong*, Nieng Yan*, Hannah-A Ledford*, Structural Basis for the Modulation of Ryanodine Receptors, Trends in Biochemical Sciences 2021, 46, 489-501