Doctor degree, professor, State laboratory of Medical Chemical Biology, graduated from Nankai University
National Science Found for Outstanding Young Scholars
Research Interest：Biosensing and Bioimaging, Sample pretreatment
Education History：
1994-1998，Chemical College, Nankai University，Bachelor of Chemistry
1998-2003，Chemical College, Nankai University，Doctor of Chemistry
Honors and Awards
Second Prize of Natural Science of Tianjin (No. 2)
The Chinese Chemical Society Young Chemistry Award
Scientific Achievements & Selected Publications
1. Dong-Xia Wang, Jing Wang*, Ya-Xin Wang ,Jia-Yi Ma, Bo Liu, An-Na Tang, De-Ming Kong*, A CRISPR/Cas12a-responsive dual-aptamer DNA network for specific capture and controllable release of circulating tumor cells. Chemical Science, 2022, 13, 10395-10405.
2. Jia-Yi Ma, Si-Yuan Wang, Yi-Chen Du, Dong-Xia Wang, An-Na Tang, Jing Wang*, De-Ming Kong*, “RESET” Effect: Random extending sequences enhance the trans-cleavage activity of CRISPR/Cas12a. Analytical Chemistry, 2022, 94, 8050-8057.
3. Dong-Xia Wang, Ya-Xin Wang, Jing Wang, Jia-Yi Ma, Bo Liu, An-Na Tang, De-Ming Kong*, MnO2 nanosheets as a carrier and accelerator for improved live-cell biosensing application of CRISPR/Cas12a. Chemical Science, 2022, 13, 4364-4371.
4. Jia-Yi Ma, Ya-Xin Wang, Yan Huang, Yi Zhang, Yun-Xi Cui*, De-Ming Kong*, Chemical-biological approaches for the direct regulation of cell-cell aggregation. Aggregate, 2022, e166.
5. Jing Wang, Jia-Yi Ma, Dong-Xia Wang, Bo Liu, Xiao Jing, Dan-Ye Chen, An-Na Tang, De-Ming Kong*, Oxidative cleavage-based three-dimensional DNA biosensor for ratiometric detection of hypochlorous acid and myeloperoxidase. Analytical Chemistry, 2021, 93, 16231-16239.
6. Dong-Xia Wang, Jing Wang, Ya-Xin Wang, Yi-Chen Du, Yan Huang, An-Na Tang, Yun-Xi Cui*, De-Ming Kong*, DNA nanostructure-based nucleic acid probes: construction and biological applications. Chemical Science, 2021, 12, 7602-7622
7. Xue-Nan Feng, Yun-Xi Cui, Jing Zhang, An-Na Tang, Han-Bin Mao*, De-Ming Kong*, Chiral interaction is a decisive factor to replace D-DNA with L-DNA aptamers. Analytical Chemistry, 2020, 92, 6470-6477.
8. Jing Wang, Dong-Xia Wang, Jia-Yi Ma, Ya-Xin Wang, De-Ming Kong*, Three-dimensional DNA nanostructures to improve the hyperbranched hybridization chain reaction. Chemical Science, 2019, 10, 9758-9767.
9. Dong-Xia Wang, Jing Wang, Yun-Xi Cui, Ya-Xin Wang, An-Na Tang, De-Ming Kong*, Nanolantern-based DNA probe and signal amplifier for tumor-related biomarker detection in living cells. Analytical Chemistry, 2019, 91, 13165-13173.
10. Yun-Xi Cui, Xue-Nan Feng, Ya-Xin Wang, Hui-Yu Pan, De-Ming Kong*, An integrated-molecular-beacon based multiple exponential strand displacement amplification strategy for ultrasensitive detection of DNA methyltransferase activity. Chemical Science, 2019, 10, 2290-2297.
